Cisco Duo Security Multi-factor Authentication (MFA) Server is a popular cloud service that provides multi-factor authentication as service to other applications. This service offers push notification, phone call, SMS among other factors of authentication. You can use Cisco Duo Security to authenticate users.
Cisco Duo Security Multi-Factor Authentication servers are supported by all the actively supported clients like Connect Tunnel (CT) on Windows/Mac/Linux platforms, and Workplace.
Refer to the Integration of SMA with Cisco Duo Security MFA Server section.