The following error will be displayed to a user's browser page when attempting to reach a back-end or downstream HTTPS server whose SSL certificate is not trusted in the appliance's list of CA certificates:
Error Invalid CA certificate file - (SSL certificate problem, verify that the CA cert is OK)
To correct this error you can either import the CA's signer's certificate in AMC > SSL Settings > CA Certificates > Backend server root certificates
OR
Disable the SSL certificate check in AMC > Services > Configure Web > Validate SSL server certificates