The Capture Client Windows Agent is not cluster-aware. It does not scan the CSV file system
If the Agent is installed on a Server cluster, we recommend you do not scan the cluster. Exclude these paths (include subfolders) with Interoperability mode exclusions:
The path of the \Cluster folder on the quorum hard disk. For example, Q:\Cluster (Quorum drive)The %Systemroot%\Cluster folder. For example, C:\Windows\Cluster\For SQL Failover Clusters, MSDTC directory in the MSDTC driveThe temp folder for the Cluster Service account. For example, exclude the \clusterserviceaccount\Local Settings\Temp\ folder from virus scanning.Capture Client : S1 Windows Agent is installed on Microsoft Server Clusters in several user environments. It is not fully tested. If you experience issues with this deployment, consult with Technical Support
In some cases, Q:\ (Quorum drive) can be unmounted. In these cases, you must exclude the volume itself:
*\Volume{volumeID}\For Example:
*\Volume{82a6ea9b-f547-46ce-8605-b8705fc04e7c}\To get the volume ID, run this PowerShell command (With admin Privledge):
Get-CimInstance Win32_Volume | Where-Object Caption -like "\\?*" | Foreach {$_.Caption.split('{')[1].split('}')[0]}For Example:

Some reference Article if you are using Endpoint Solutions on machine running SQl Server/ Cluster Services.
Configuring Antivirus Software for SQL Server Environments
Cluster-aware antivirus is recommended for smooth Cluster Operation