This guide provides exclusion recommendations for applications that might cause compatibility problems or slowdowns. Use these recommendations if you encounter issues with a specific program.
The exclusion recommendations are based on field experience and recommendations from vendors. Use them if you experience interoperability issues or performance degradation from a specific application.
Create Capture Client PATH Exclusion With Exclusion Mode as Interoperability.
Folder & Subfolder Exclusion :

File Exclusion :

Paths and Files to Exclude
Based on this Microsoft article.
When you make a path exclusion, we highly recommend that you add the exclusion to the smallest relevant scope of endpoints - a specific group. For example, do not add exclusions to the default policy of the default group. Create a group of endpoints that use the application to exclude.